Born in Albion, Maine on January 30, 1835, Edmund Fuller Webb was educated at Freedom, China and Waterville Academies, graduating from what was then called Waterville College in 1856.
Following that graduation he studied law in both Albion and Portland before being admitted to the Cumberland County Bar in 1859.
After opening a practice in Albion, he moved one year later to Waterville where he continued a successful law practice for the remainder of his life.
He was elected to the Maine House of Representatives for two terms, serving as Speaker of the House in 1873. In the latter year was elected President of the Senate.
Webb was chosen County Attorney for Kennebec in 1878 and served in that post for the next three years.
Among his other accomplishments, he was a trustee of Colby College, a director of the Waterville Bank and a solicitor for the Maine Central Railroad.